The position of importance is not change though now that 20 years have passed since Virtua Fighter 1. The strategy of 2-Alternative Forced Choice based on frames has been the essential and basic part.
The 2AFC describes a situation in which you have enough advantage in frames to force the opponent to choose between two alternatives. In other words, a forced choice is available at 6 frames or better, because there are no simple technique to defend against both a Mid Attack and a fast Throw. On the other hand, it seems likely that traditional 2-Choice Offense is largely impotent against the Fuzzy Guarding at small advantage. How should we treat the small advantage? Representative countermeasures are shown below:
It is essential that we pay attention to the Delayed 2-Choice Offence (action 4). You might have an experience in which countermeasures against Fuzzy Guarding fell an easy prey to Abare (attacks from disadvantage) Player without fear or hesitation.
Indeed, Fuzzy Guarding will be thwarted if you slightly delays the throw attempt rather than doing it at the earliest possible moment. However, a delayed Mid Attacks (as well as a Throw) would make you vulnerable to opponent’s Abare.
A Biting Aphorism: Fuudo, a top Virtua Fighter
All that he says is perfectly correct. However, the most important message would be “we should be able to do actions based on frames.” However, it seems likely that many intermediate players haven't achieved the essential things. If a player would neglect 2AFC based on classical techniques, he could not make himself steady against intermediate while he might win senior accidentally. We have to maintain a proper balance between development and conservation.
A Biting Aphorism: ItabashiZangief, a top Virtua Fighter
All of senior players are requested to perform exceptional measures as the 3rd choice, but there would be multiple advanced techniques as a candidate. You have to know how to choose the most efficient technique under the certain conditions. Let's start again by using the character who has a natural 3rd choice if your results are stagnating.
The list above should be used only as a guideline in order to acquire necessary knowledge or a technique. There is, if any, little difference among character in Virtua Fighter. There are many ways to become experts, but the most straightforward is that the precious character will be with you, always.
A Biting Aphorism: Kumicho, a top Virtua Fighter
 Advantage and Disadvantage
 VF5FS 初心者向け情報ブログ: ttp://vf5fsbeginner.blog.fc2.com/blog-entry-34.html
 Fuzzy Guarding 1
 High Throws at Large Advantage 1
 Catch Throws and Guard Break Attacks 1
 High Throws at Large Advantage 3
 Fuzzy Guarding 2
 Attack Levels 2
 2AFC Approach: Preface
 八極拳に入門してみた！: ttp://blog.livedoor.jp/hougeki/archives/1348353.html
 Catch Throws and Guard Break Attacks 4